Team Metabolic Health

Obesity,Oxidative Stress,Stress

Study reveals that an 11-week, very-low-calorie ketogenic diet significantly reduces body fat and improves glucose metabolism in obese individuals, while also lowering oxidative stress markers, indicating better overall metabolic health.

A study published in the journal Free Radical Biology and Medicine demonstrates the impact of a multiphase, very-low-calorie ketogenic diet on serum markers of oxidative stress in individuals living with obesity.

Calorie-restricted diets with high levels of nutraceuticals and phytochemicals have been found to reduce obesity-related complications and increase life expectancy through anti-inflammatory and antioxidant activities. Important observations The analysis of baseline characteristics identified dyslipidemia as the most frequent comorbidity among participants. All of them were physically active; however, their activity levels were low.

Regarding metabolic effects, the intervention was found to improve glucose and lipid metabolism, with no changes in serum total protein and albumin levels. Study significance The study finds that intake of a multiphase, very-low-calorie ketogenic diet for eleven weeks has positive health effects, as demonstrated by reduced body weight and fat mass and improved glucose and lipid metabolism. These positive health effects are associated with reduced serum oxidative stress markers and improved serum redox balance.

Credit: Head Topics (UK)