Team Metabolic Health Understanding how carnitine transporters regulate sperm motility and hormone production could unlock new fertility treatments, offering hope for millions affected by infertility globally. Carnitine transport mediated by multiple SLCs is depicted with different colors. The transport of carnitine across epithelial cells of the intestine, kidney, and placenta, as well as into the […]
GLP-1 drugs protect brain health by improving neurovascular function and reducing inflammation
Team Metabolic Health New research reveals how GLP-1 receptor drugs, known for treating diabetes and obesity, also protect the brain’s vital neurovascular system, offering hope for tackling cognitive decline and neurodegenerative diseases like Alzheimer’s. In a recent review published in the journal Cell Metabolism, a group of authors explored how Glucagon-Like Peptide-1 receptor (GLP-1R) agonism shapes […]
Living with obesity – and what it means for your heart and general health
Team Metabolic Health Obesity is a risk factor for a number of complications. Some of these are cardiovascular, a group that includes coronary artery disease, high blood pressure, stroke, hyperlipidaemia, heart attack and heart failure.1 Obesity is also a leading cause of cardiovascular mortality and morbidity.1 Here is the good news: With appropriate action, supported by professional […]
Bitter pill: 20% of doctors obese, 53% diabetic, 24% hypertensive
Team Metabolic Health SURVEY POINTS TO HIGH PREVALENCE OF LIFESTYLE DISEASES AMONG DOCS Ahmedabad : They are advocates of balanced diet, exercise and healthy lifestyle, but a study conducted in the state reveals high prevalence of lifestyle diseases among doctors.The MP Shah Medical College in Jamnagar surveyed 490 doctors working in govt facilities and found that […]
Is Nighttime Depression Really a Thing?
Team Metabolic Health There are lots of reasons your mood might tank at night. Here’s how to address the bedtime blues. It’s not uncommon for our minds to unleash a torrent of difficult feelings under the cover of darkness: sadness and negative thoughts may surface at night, making sleep hard to come by. On social media and […]
Obesity real risk for blood sugar: Why weight loss drugs are preventing other diseases too
Team Metabolic Health Here are key takeaways from latest research and a session of the European Association of the Study of Diabetes (EASD) If there is one takeaway from latest research and the European Association of the Study of Diabetes (EASD) session in Madrid, which I attended, it is that researchers are unanimous about the […]
Novo’s GLP-1 Wegovy could improve heart health for millions more than previously thought, AI study finds
Team Metabolic Health Through real-world data, an AI company found that popular weight loss drugs could be a preventive measure for patients at risk of heart attack and stroke. Novo Nordisk got a major boost in March when the FDA approved its GLP-1 diabetes and weight loss drug Wegovy to also prevent heart attacks and strokes in […]
As AI transforms drug development, biotechs might not need as much Big Pharma support
Team Metabolic Health Small biotechs are making gains with AI drug development, and their advantages may help some push ahead without Big Pharma. AI is making its mark on the pharma market, presenting opportunities for Big Pharma to cut down on drug development costs and fast-track new discoveries. But AI’s capabilities also open the door […]
AI Simulations Help Drug Trials
Team Metabolic Health Artificial intelligence (AI) has been revolutionizing much of early drug discovery, yet human clinical trials remain a bottleneck. Now some applications of the new technologies are bringing efficiencies to clinical research. Sophisticated modeling and simulations suggests that AI can play a major role in improving the success rates of novel drugs entering […]
Novo and Lilly contender Zealand Pharma heralds its obesity drug alternative: It’s our ‘crown jewel’
Team Metabolic Health Key Points Jaap Arriens | NurPhoto Danish biotech Zealand Pharma is targeting the “next generation” of weight loss drugs as competitors pile into a market dominated by heavyweights Novo Nordisk and Eli Lilly. CEO Adam Steensberg told CNBC Thursday that early-stage trials of its experimental obesity injection point to higher-quality weight loss — with reduced muscle loss and […]
Muscle loss and protein needs in older adults
Team Metabolic Health It’s not your imagination: it is harder to gain — or just maintain — muscle after middle age. Aging brings many changes to the body. One such change is muscle loss. Adults who don’t engage in regular strength training can lose 4 to 6 pounds of muscle per decade. The technical term […]
How — and why — to fit more fiber and fermented food into your meals
Team Metabolic Health Fiber and fermented foods aid the gut microbiome, contributing to better health and mood. An F may mean failure in school, but the letter earns high marks in your diet. The two biggest dietary Fs — fiber and fermented foods — are top priorities to help maintain healthy digestion, and they potentially […]
Ratan Tata’s legacy: Revolutionising cancer care in India, one hospital at a time
Team Metabolic Health The Tata Group’s foray into healthcare began in 1941 with the establishment of the Tata Memorial Hospital in Mumbai. There is a reason why the titan Ratan Tata, who led over 30 companies in more than 100 countries, was never featured in the list of “billionaires” of the world or India. Today, […]
The golden era of GLP-1 drugs: Where we are and what comes next
Team Metabolic Health Glucagon-like peptide 1 (GLP-1) receptor agonists (RAs) are entero-pancreatic hormone-based treatments first approved in 2005 for type 2 diabetes (T2D). They are now commonly prescribed for weight loss and reduction of atherosclerotic cardiovascular (CV) risk in patients with T2D. The health benefits and market success of GLP-1 drugs are a hot topic in […]
Is the portfolio diet the best diet ever?
Maybe — but that could be the wrong question. Team Metabolic Health What we eat can play a pivotal role in warding off — or treating — disease and enhancing quality of life. You may already believe this, and certainly mounting evidence supports that idea. But on the cluttered shelf of diets claiming top health benefits, which […]
