Team Metabolic Health As drug companies fret over their finances, they are increasingly partnering with universities to help with early-stage research Pharmaceutical companies are often lambasted for rising drug costs. For example, the price of new drugs entering the US market in 2023 was 35% higher than in 2022. According to an analysis from Reuters, part […]
World First: Stem Cells Reverse Type 1 Diabetes in Clinical Trial
Team Metabolic Health Most people with type 1 diabetes cannot reverse their autoimmune disease or put it into spontaneous remission – all they can do is manage their blood sugar levels with insulin, a healthy diet, and regular exercise. Now, the successful treatment of the condition in a young woman in China has brought the possibility of a universal cure […]
Gene-editing drugs are moving from lab to clinic at lightning speed
Team Metabolic Health One autumn day in 2020 Patrick Doherty was walking his dog up a steep mountain in County Donegal, Ireland, when he noticed he was, unusually for him, running out of breath. The eventual diagnosis was terrifying: amyloidosis, a rare genetic disease that caused a protein, amyloid, to build up in his organs […]
Weight loss and diabetes – Know each and everything
Team Metabolic Health Weight is a sensitive issue for many people and getting to an ideal, healthy weight is easier said than done. But when you have diabetes, there are huge benefits to losing weight if you’re carrying extra weight. You’ll have more energy and you’ll reduce your risk of serious complications like heart disease […]
Lilly releases Zepbound® (tirzepatide) single-dose vials, expanding supply and access for adults living with obesity
Team Metabolic Health Eli Lilly and Company (NYSE: LLY) today announced Zepbound® (tirzepatide) 2.5 mg and 5 mg single-dose vials are available for self-pay for patients with an on-label prescription, significantly expanding the supply of Zepbound in response to high demand. The single-dose vials are priced at a 50% or greater discount compared to the list price of all […]
How carnitine transporters boost reproductive health
Team Metabolic Health Understanding how carnitine transporters regulate sperm motility and hormone production could unlock new fertility treatments, offering hope for millions affected by infertility globally. Carnitine transport mediated by multiple SLCs is depicted with different colors. The transport of carnitine across epithelial cells of the intestine, kidney, and placenta, as well as into the […]
GLP-1 drugs protect brain health by improving neurovascular function and reducing inflammation
Team Metabolic Health New research reveals how GLP-1 receptor drugs, known for treating diabetes and obesity, also protect the brain’s vital neurovascular system, offering hope for tackling cognitive decline and neurodegenerative diseases like Alzheimer’s. In a recent review published in the journal Cell Metabolism, a group of authors explored how Glucagon-Like Peptide-1 receptor (GLP-1R) agonism shapes […]
Living with obesity – and what it means for your heart and general health
Team Metabolic Health Obesity is a risk factor for a number of complications. Some of these are cardiovascular, a group that includes coronary artery disease, high blood pressure, stroke, hyperlipidaemia, heart attack and heart failure.1 Obesity is also a leading cause of cardiovascular mortality and morbidity.1 Here is the good news: With appropriate action, supported by professional […]
Bitter pill: 20% of doctors obese, 53% diabetic, 24% hypertensive
Team Metabolic Health SURVEY POINTS TO HIGH PREVALENCE OF LIFESTYLE DISEASES AMONG DOCS Ahmedabad : They are advocates of balanced diet, exercise and healthy lifestyle, but a study conducted in the state reveals high prevalence of lifestyle diseases among doctors.The MP Shah Medical College in Jamnagar surveyed 490 doctors working in govt facilities and found that […]
Is Nighttime Depression Really a Thing?
Team Metabolic Health There are lots of reasons your mood might tank at night. Here’s how to address the bedtime blues. It’s not uncommon for our minds to unleash a torrent of difficult feelings under the cover of darkness: sadness and negative thoughts may surface at night, making sleep hard to come by. On social media and […]
Obesity real risk for blood sugar: Why weight loss drugs are preventing other diseases too
Team Metabolic Health Here are key takeaways from latest research and a session of the European Association of the Study of Diabetes (EASD) If there is one takeaway from latest research and the European Association of the Study of Diabetes (EASD) session in Madrid, which I attended, it is that researchers are unanimous about the […]
Novo’s GLP-1 Wegovy could improve heart health for millions more than previously thought, AI study finds
Team Metabolic Health Through real-world data, an AI company found that popular weight loss drugs could be a preventive measure for patients at risk of heart attack and stroke. Novo Nordisk got a major boost in March when the FDA approved its GLP-1 diabetes and weight loss drug Wegovy to also prevent heart attacks and strokes in […]
As AI transforms drug development, biotechs might not need as much Big Pharma support
Team Metabolic Health Small biotechs are making gains with AI drug development, and their advantages may help some push ahead without Big Pharma. AI is making its mark on the pharma market, presenting opportunities for Big Pharma to cut down on drug development costs and fast-track new discoveries. But AI’s capabilities also open the door […]
AI Simulations Help Drug Trials
Team Metabolic Health Artificial intelligence (AI) has been revolutionizing much of early drug discovery, yet human clinical trials remain a bottleneck. Now some applications of the new technologies are bringing efficiencies to clinical research. Sophisticated modeling and simulations suggests that AI can play a major role in improving the success rates of novel drugs entering […]
Novo and Lilly contender Zealand Pharma heralds its obesity drug alternative: It’s our ‘crown jewel’
Team Metabolic Health Key Points Jaap Arriens | NurPhoto Danish biotech Zealand Pharma is targeting the “next generation” of weight loss drugs as competitors pile into a market dominated by heavyweights Novo Nordisk and Eli Lilly. CEO Adam Steensberg told CNBC Thursday that early-stage trials of its experimental obesity injection point to higher-quality weight loss — with reduced muscle loss and […]
